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Results 2

FOCUS  III (lesion)

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figure3

Figure 3 Pattern of activity in an array of 24 by 24 columns. Only the pattern of activity in excitatory neurons in the array is shown (216 x 216 neurons). The simulated "lesion" (40% of excitatory synapses are inactive) covers the area of 6 by 12 columns. The network was activated by background action potentials applied on inputs of all neurons at t=0. The activity in the network continues without additional background input. The mechanism of self-sustained activity relays on neurons in the "lesion" that do not fire synchronously and are in phase with neurons in the surrounding area. In the surrounding area neurons fire synchronous bursts followed by a refractory period caused by AHP. The activity in the "lesion" continues until neurons in the surrounding area recover from AHP and hence induce recurrent and  synchronous bursts in the network.



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Next: Conclusions Up: index Previous: Results 1